Edward H. Shortliffe is Chair Emeritus and Adjunct Professor in the Department of Biomedical Informatics at Columbia University’s Vagelos College of Physicians and Surgeons. He is also Adjunct Professor of Biomedical Informatics in the College of Health Solutions at Arizona State University and Adjunct Professor of Population Health Sciences (Health Informatics) at Weill Cornell Medical College. Previously he served as President and Chief Executive Officer of the American Medical Informatics Association. He has also held academic appointments at the University of Texas Health Sciences Center in Houston, and the University of Arizona. He chaired the Department of Biomedical Informatics at Columbia (2000-2007), and the Section on Medical Informatics at Stanford University (1979-2000). A pioneer in the development of applications of artificial intelligence in medicine, including the first expert system (MYCIN), he has also spearheaded the formation and evolution of graduate degree programs in biomedical informatics at Stanford, Columbia, and Arizona State University. Both a PhD informatics scientist and a physician who has practiced internal medicine, Dr. Shortliffe is an elected member of the National Academy of Medicine. He has also been elected to fellowship in the American College of Medical Informatics (ACMI), the Association for the Advancement of Artificial Intelligence (AAAI), and the International Academy for Health Sciences Informatics (IAHSI). A Master of the American College of Physicians, he received the Association of Computing Machinery’s Grace Murray Hopper Award in 1976 and ACMI’s Morris F. Collen Award in 2006. Editor Emeritus of the Journal of Biomedical Informatics and editor of a well-known textbook on Biomedical Informatics (now in its fifth edition), Dr. Shortliffe has authored over 375 articles and books in the fields of biomedical informatics and artificial intelligence.